Searchable abstracts of presentations at key conferences on calcified tissues

ba0004p128 | (1) | ICCBH2015

Patients treated with anti-epileptic drugs have a higher rate of fracture and impaired bone and muscle development compared with controls: results from a pilot study

Simm Peter J , Seah Sebastian , Mackay Mark , Freeman Jeremy , Petty Sandra J , Wark John D

Epilepsy is a relatively common condition of childhood, with anti-epileptic drugs (AEDs) the mainstay of medical therapy. AED use in adults has been shown to be associated with impaired bone density and increased risk of bone fracture. Paediatric data are more limited particularly in relation to fracture risk and skeletal geometry.This study aimed to examine the within-pair differences in fracture prevalence and bone, muscle and balance parameters in sex...

ba0005lb3 | (1) | ECTS2016

Peripheral quantitative computed tomography measures contribute to the understanding of bone fragility in low-trauma fracture patients

Jiang Hongyuan , Yates Christopher , Gorelik Alexandra , Kale Ashwini , Song Qichun , Wark John D

Background and aims: Dual energy X-ray absorptiometry (DXA) as currently utilised has limitations in identifying patients with osteoporosis and predicting fractures, since most low-trauma fracture (LTF) patients have osteopenia not osteoporosis based on DXA assessment. We aimed to express peripheral quantitative computed tomography (pQCT) variables of patients with low-trauma fracture as T-scores by using T-score scales obtained from healthy young women, and ...